Instance ID10172
Regular ExpressionxKENx
Motif InstanceVKENL
Bait Uniprot AccessionQ08981
Bait Uniprot IdentifierACM1_YEAST
Bait Gene NameACM1
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position97-101
Critical ResiduesP2; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20172
Interacting DomainWD40 repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18596038
CommentsKEN box motif in budding yeast Acm1 protein that is required for high affinity interaction with the substrate receptor site on the WD40 domain of Cdh1 that may serve both to promote APC inhibition and protect Acm1 from destruction

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)