Instance ID10173
Regular ExpressionxKENx
Motif InstanceAKENE
Bait Uniprot AccessionO60566
Bait Uniprot IdentifierBUB1B_HUMAN
Bait Gene NameBUB1B
Bait OrganismHomo sapiens (Human)
Sequence Position303-307
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20173
Interacting DomainWD40 repeat domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)22193957
CommentsSecond KEN-box motif (303-307) of human Mitotic checkpoint kinase BUB1 beta, a subunit of the Spindle Assembly Checkpoint (SAC),that binds to the substrate recruitment site of human CDC20, the substrate recognition subunit of the Anaphase Promoting Complex/Cyclosome (APC/C), thereby blocking the recruitment of substrates to the APC/C

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)