Instance ID10176
Regular Expressionx[ILM]R$
Motif InstanceNLR
Bait Uniprot AccessionQ8NI77
Bait Uniprot IdentifierKI18A_HUMAN
Bait Gene NameKIF18A
Bait OrganismHomo sapiens (Human)
Sequence Position896-898
Critical ResiduesP2; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Fluorescence microscopy; RNA interference; Mutation disrupting interaction; Ubiquitinase assay; Western blot; Co-IP; Mutation analysis
Interaction ID20176
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23288039
CommentsC‐terminal LR motif in Kinesin-like protein KIF18A is required for Kif18A degradation at anaphase through interaction with APC/C–Cdc20

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)