Instance ID10187
Regular Expressionx[ILM]R$
Motif InstanceRIR
Bait Uniprot AccessionQ9UM11
Bait Uniprot IdentifierFZR_HUMAN
Bait Gene NameFZR1
Bait OrganismHomo sapiens (Human)
Sequence Position494-496
Critical ResiduesP2; P3
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation disrupting interaction; Cross linking studies; Mutation analysis; Ubiquitinase assay; Peptide binding to perpetrator; Competition binding; Pull down
Interaction ID20187
Interacting DomainTetratricopeptide repeats
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15916961, 12956947
CommentsConserved C-terminal motif found in human CDH1 that mediates binding to the TPR domain in APC3

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)