Instance ID10190
Regular Expression[DE]R[YFH][ILFVM][PAG]xR
Motif InstanceDRYIPHR
Bait Uniprot AccessionQ12834
Bait Uniprot IdentifierCDC20_HUMAN
Bait Gene NameCDC20
Bait OrganismHomo sapiens (Human)
Sequence Position77-83
Critical ResiduesP1; P2; P3; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20190
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19026787
CommentsA short, highly conserved motif in human CDC20 that possibly interacts with the catalytic Apc2 subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)