Instance ID10216
Regular Expressionx(S)xxF
Motif InstanceQSPTF
Bait Uniprot AccessionQ13085
Bait Uniprot IdentifierACACA_HUMAN
Bait Gene NameACACA
Bait OrganismHomo sapiens (Human)
Sequence Position1262-1266
Critical ResiduesP2; P5
Motif PTM(s)Phosphorylation at Ser-P2
Secondary StructureUnknown
Experimental Method(s)X-ray crystallography; Co-IP; Pull down
Interaction ID20216
Interacting DomainBRCT domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18452305, 16698035
CommentsPhosphorylated serine (pS) sequence in human Acetyl-CoA carboxylase 1 (ACACA) that mediates specific interaction with the carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)