Instance ID10240
Regular Expressionx[NP]W[DES]xW
Motif InstanceIPWDLW
Bait Uniprot AccessionO00499
Bait Uniprot IdentifierBIN1_HUMAN
Bait Gene NameBIN1
Bait OrganismHomo sapiens (Human)
Sequence Position415-420
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)Mutation analysis; Western blot; Pull down
Interaction ID20240
Interacting DomainClathrin propeller repeat
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9603201
Comments"Variant clathrin box motif (W box) in human Amphiphysin II (BIN1) that are found in tandem arrangement with a ""classical"" clathrin box and cooperate to effect optimal clathrin binding and the formation of sedimentable assemblies"

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)