Instance ID10251
Regular Expression[NQ]{0,1}xx[ILMV][ST][DEN][FY][FY]x{2,3}[KR]{2,3}[^DE]
Motif InstancePLISDFFAKRKRS
Bait Uniprot AccessionP49918
Bait Uniprot IdentifierCDN1C_HUMAN
Bait Gene NameCDKN1C
Bait OrganismHomo sapiens (Human)
Sequence Position270-282
Critical ResiduesP5; P7; P9; P10
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID20251
Interacting DomainPCNA, C-terminal domain
Disease Association(s)IMAGe syndrome
Inhibitor(s)Unknown
Reference(s)22634751
CommentsPIP box motif in human Cyclin-dependent kinase inhibitor p57 (CDKN1C) that is required to bind PCNA

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)