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Instance ID | 10252 | Regular Expression | [NQ]{0,1}xx[ILMV][ST][DEN][FY][FY]x{2,3}[KR]{2,3}[^DE] | Motif Instance | RRVTDFFARRRP | Bait Uniprot Accession | Q9H211 | Bait Uniprot Identifier | CDT1_HUMAN | Bait Gene Name | CDT1 | Bait Organism | Homo sapiens (Human) | Sequence Position | 4-15 | Critical Residues | Unknown | Motif PTM(s) | Unknown | Secondary Structure | Alpha helix | Experimental Method(s) | RNA interference;Western blot; Co-IP | Interaction ID | 20252 | Interacting Domain | PCNA, C-terminal domain | Disease Association(s) | Unknown | Inhibitor(s) | Unknown | Reference(s) | 16861906 | Comments | The human homologue of Drosophila L2DTL or fission yeast CDT2 (DTL) interacts with PCNA and regulates human DNA replication factor CDT1 proteolysis in response to DNA damage, through the conserved PIP box motif |
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