|
| Instance ID | 10256 | | Regular Expression | [NQ]{0,1}xx[ILMV][ST][DEN][FY][FY]x{2,3}[KR]{2,3}[^DE] | | Motif Instance | RKLTDFYPVRRS | | Bait Uniprot Accession | Q9NQR1 | | Bait Uniprot Identifier | SETD8_HUMAN | | Bait Gene Name | SETD8 | | Bait Organism | Homo sapiens (Human) | | Sequence Position | 220-231 | | Critical Residues | P6; P7 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | RNA interference;Western blot; Co-IP; Alanine scanning; Fluorescence technology; Mutation disrupting interaction; Ubiquitinase assay | | Interaction ID | 20256 | | Interacting Domain | PCNA, C-terminal domain | | Disease Association(s) | Unknown | | Inhibitor(s) | Unknown | | Reference(s) | 20932472, 21220508 | | Comments | CDT2-mediated destruction of the histone methyltransferase SETD8 prevents premature chromatin compaction in S phase |
|
