Instance ID10261
Regular Expression([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR])))
Motif InstancePVDLS
Bait Uniprot AccessionO95600
Bait Uniprot IdentifierKLF8_HUMAN
Bait Gene NameKLF8
Bait OrganismHomo sapiens (Human)
Sequence Position86-90
Critical ResiduesP3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down
Interaction ID20261
Interacting DomainD-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10756197
CommentsHuman Krüppel-like factor 8 contains a Pro-Val-Asp-Leu-Ser/Thr motif that mediates contact with the co-repressor protein C-terminal Binding Protein (CtBP) and represses transcription


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)