Instance ID10268
Regular Expression([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR])))
Motif InstancePLDLS
Bait Uniprot AccessionQ15583
Bait Uniprot IdentifierTGIF1_HUMAN
Bait Gene NameTGIF1
Bait OrganismHomo sapiens (Human)
Sequence Position153-157
Critical ResiduesP1; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine scanning
Interaction ID20268
Interacting DomainD-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Disease Association(s)Holoprosencephaly
Inhibitor(s)Unknown
Reference(s)10995736
CommentsThe homeodomain protein TGIF1 interacts with the transcriptional corepressor CtBP via the PxDLS motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)