Instance ID10284
Regular Expression([P][LVIPME][DENS][LM][VASTRG])|([G][LVIPME][DENS][LM][VASTRG]((K)|(x[KR])))
Motif InstancePLDLS
Bait Uniprot AccessionP03254
Bait Uniprot IdentifierE1A_ADE02
Bait Gene NameNot Available
Bait OrganismHuman adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
Sequence Position279-283
Critical ResiduesP1; P2; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Pull down; Co-IP; Mutation analysis
Interaction ID20284
Interacting DomainD-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)7479821
CommentsC-terminal binding protein (CtBP) interacts with a conserved C-terminal motif of adenovirus E1A (exon 2), which may play a critical role in adenovirus replication and oncogenic transformation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)