Instance ID10286
Regular Expression[RK]xLx{0,1}[FYLIVMP]
Motif InstanceRNLL
Bait Uniprot AccessionQ99640
Bait Uniprot IdentifierPMYT1_HUMAN
Bait Gene NamePKMYT1
Bait OrganismHomo sapiens (Human)
Sequence Position486-489
Critical ResiduesP1; P2; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20286
Interacting DomainCyclin, N-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10373560
CommentsThe cyclin recognition site (RxL motif) found in human Myt1 kinase that interacts with cyclin B1 and thereby induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)