Instance ID10289
Regular Expression[RK]xLx{0,1}[FYLIVMP]
Motif InstanceRSLF
Bait Uniprot AccessionP49918
Bait Uniprot IdentifierCDN1C_HUMAN
Bait Gene NameCDKN1C
Bait OrganismHomo sapiens (Human)
Sequence Position31-34
Critical ResiduesP1
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis
Interaction ID20289
Interacting DomainUnknown
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10713702
CommentsHuman Cyclin-dependent kinase inhibitor p57Kip2 associates with itself by using the NH2 terminal domain to form a homodimeric species which interacts with and inhibits the cyclin D1-Cdk4 complexes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)