Instance ID10291
Regular Expression[RK]xLx{0,1}[FYLIVMP]
Motif InstanceKKLF
Bait Uniprot AccessionQ9WTQ5
Bait Uniprot IdentifierAKA12_MOUSE
Bait Gene NameAkap12
Bait OrganismMus musculus (Mouse)
Sequence Position501-504
Critical ResiduesP1
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis
Interaction ID20291
Interacting DomainCyclin, N-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10982843
CommentsSSeCKS, a major protein kinase C substrate with tumor suppressor activity, regulates G(1)-->S progression by controlling the expression and cellular compartmentalization of cyclin D through a physical association with cyclin D via its RxL motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)