Instance ID10300
Regular Expression[RK]xLx{0,1}[FYLIVMP]
Motif InstanceRRLF
Bait Uniprot AccessionP06789
Bait Uniprot IdentifierVE1_HPV18
Bait Gene NameE1
Bait OrganismHuman papillomavirus type 18
Sequence Position127-130
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Western blot; Pull down; Mutation analysis
Interaction ID20300
Interacting DomainCyclin, N-terminal domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9892642
CommentsThe cyclin interaction motif (RXL motif) in the human papillomavirus (HPV) DNA replication initiation protein E1 that mediates its interaction with Cyclin E for phosphorylation by Cyclin E/Cdk2 Complex

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)