Instance ID10310
Regular Expression[^P]x[KR]xTQT
Motif InstanceCDKSTQT
Bait Uniprot AccessionO43521
Bait Uniprot IdentifierB2L11_HUMAN
Bait Gene NameBCL2L11
Bait OrganismHomo sapiens (Human)
Sequence Position50-56
Critical ResiduesP2; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Co-IP; Mutation analysis
Interaction ID20310
Interacting DomainDynein light chain type 1
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10198631, 12591950
CommentsDynein (Light Chain) binding KxTQT motif in Isoform Bim(L) of human Bcl-2-like protein 11 (BCL2L11)/ Bcl2-interacting mediator of cell death (BIM) that binds to DLC-8 to neutralize its antiapoptotic activity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)