Instance ID10318
Regular ExpressionxNPFx
Motif InstanceTNPFL
Bait Uniprot AccessionP52594
Bait Uniprot IdentifierAGFG1_HUMAN
Bait Gene NameAGFG1
Bait OrganismHomo sapiens (Human)
Sequence Position558-562
Critical ResiduesP2; P3; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Classical fluorescence spectroscopy; Display technology; Pull down; SPR; NMR
Interaction ID20318
Interacting DomainEH domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9303539, 9446614, 9721102, 11062555
CommentsAsn-Pro-Phe motif (558-562) in human Arf-GAP domain and FG repeat-containing protein 1 that is responsible for the interaction with Eps15 homology (EH) domain of Epidermal growth factor receptor substrate 15 (EPS15)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)