Instance ID10409
Regular ExpressionYxxxxL[VILMF]
Motif InstanceYGPTFLL
Bait Uniprot AccessionP39935
Bait Uniprot IdentifierIF4F1_YEAST
Bait Gene NameTIF4631
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position452-458
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down(GST tag)
Interaction ID20409
Interacting DomainEukaryotic initiation factor 4E
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9118949
CommentsYxxxxL motif in yeast Eukaryotic initiation factor 4F subunit p150 (eIF4G1) that mediate binding to the dorsal surface of eIF4E, a key regulator of eukaryotic cap-dependent translation, and play a role in translation initiation, via interactions with eIF4G

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)