Instance ID10410
Regular ExpressionYxxxxL[VILMF]
Motif InstanceYGPTFLL
Bait Uniprot AccessionP39936
Bait Uniprot IdentifierIF4F2_YEAST
Bait Gene NameTIF4632
Bait OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Sequence Position423-429
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Pull down(GST tag)
Interaction ID20410
Interacting DomainEukaryotic initiation factor 4E
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9118949
CommentsYxxxxL motif in yeast Eukaryotic initiation factor 4F subunit p130 (eIF4G2) that mediate binding to the dorsal surface of eIF4E, a key regulator of eukaryotic cap-dependent translation, and play a role in translation initiation, via interactions with eIF4G

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)