Instance ID10414
Regular ExpressionYxxxxL[VILMF]
Motif InstanceYDRKFLL
Bait Uniprot AccessionQ13542
Bait Uniprot Identifier4EBP2_HUMAN
Bait Gene NameEIF4EBP2
Bait OrganismHomo sapiens (Human)
Sequence Position54-60
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Pull down; SPR
Interaction ID20414
Interacting DomainEukaryotic initiation factor 4E
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10406811
CommentsThe eIF4E binding motif found in human 4E-BP2, a member of the family of Inhibitors of translation initiation known as eIF4E-binding proteins (4E-BPs), which competitively bind and sequester the available eIF4E thereby preventing eIF4F complex formation

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)