Instance ID10419
Regular ExpressionYxxxxL[VILMF]
Motif InstanceYDREFLL
Bait Uniprot AccessionO43432
Bait Uniprot IdentifierIF4G3_HUMAN
Bait Gene NameEIF4G3
Bait OrganismHomo sapiens (Human)
Sequence Position624-630
Critical ResiduesP1; P6
Motif PTM(s)Unknown
Secondary StructureDisordered
Experimental Method(s)ITC; X-ray crystallography
Interaction ID20419
Interacting DomainEukaryotic initiation factor 4E
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)10394359
CommentsThe eIF4E binding motif found in human Eukaryotic translation initiation factor 4 gamma 3 (EIF4G3) that is critical for the interaction with EIF4E

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)