Instance ID10448
Regular ExpressionPPxxF
Motif InstancePPHHF
Bait Uniprot AccessionP21817
Bait Uniprot IdentifierRYR1_HUMAN
Bait Gene NameRYR1
Bait OrganismHomo sapiens (Human)
Sequence Position1773-1777
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Western blot; Pull down; Co-IP
Interaction ID20448
Interacting DomainWH1 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12223488
CommentsProline-rich motif in human Ryanodine receptor 1 that is recognized by Class II EVH1 domain of Homer1 by which Homer directly modulates the function of its target protein RyR1 and excitation-contraction coupling in skeletal myotubes

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)