Instance ID10451
Regular Expression[FY]x[FW]xxxxx[LMVIF]PxP[DE]
Motif InstanceYSFHPVEDFPAPE
Bait Uniprot AccessionQ8TF74
Bait Uniprot IdentifierWIPF2_HUMAN
Bait Gene NameWIPF2
Bait OrganismHomo sapiens (Human)
Sequence Position400-412
Critical ResiduesP1; P3; P8; P9
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Alanine scanning
Interaction ID20451
Interacting DomainWH1 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)15265696, 12213210
CommentsThe EVH1 class III motif found in the human verprolin homologue WIRE (WIPF2) that participates in binding to human Wiskott-Aldrich syndrome protein (WASP)

© 2014 Bose Institute, Kolkata. All rights reserved

For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)