Instance ID10453
Regular Expression[FY]x[FW]xxxxx[LMVIF]PxP[DE]
Motif InstanceFYFHPISDLPPPE
Bait Uniprot AccessionO43516
Bait Uniprot IdentifierWIPF1_HUMAN
Bait Gene NameWIPF1
Bait OrganismHomo sapiens (Human)
Sequence Position454-466
Critical ResiduesP1; P3; P8; P9; P12
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Western blot; NMR; Mutation analysis; structure based prediction; Alanine scanning; GFP tag; Pull down
Interaction ID20453
Interacting DomainWH1 domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12437929, 17229736, 12372256
CommentsThe rat N-WASP EVH1 domain specifically binds an EVH1 class III motif from the human WASP Interacting Protein (WIP or WIPF1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)