Instance ID10455
Regular Expression[DE]HxY
Motif InstanceDHPY
Bait Uniprot AccessionQ9NWW0
Bait Uniprot IdentifierHPIP_HUMAN
Bait Gene NameHCFC1R1
Bait OrganismHomo sapiens (Human)
Sequence Position76-79
Critical ResiduesP1; P2; P4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Y2H; Mutation analysis
Interaction ID20455
Interacting DomainGalactose oxidase, central domain
Disease Association(s)Herpes simplex virus (HSV) infection
Inhibitor(s)Unknown
Reference(s)12235138
CommentsInteraction of human Host cell factor 1 (HCF-1) with a HCF-1 beta-propeller domain binding protein, termed HPIP, mediated by a HCF-binding motif or HBM in HPIP, through which HPIP regulates HCF-1 activity by modulating its subcellular localization

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)