Instance ID10456
Regular Expression[DE]HxY
Motif InstanceDHDY
Bait Uniprot AccessionQ16254
Bait Uniprot IdentifierE2F4_HUMAN
Bait Gene NameE2F4
Bait OrganismHomo sapiens (Human)
Sequence Position389-392
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Co-IP; Mutation analysis
Interaction ID20456
Interacting DomainGalactose oxidase, central domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)16633736
CommentsTranscription factor E2F4 specifically and directly interacts with human Host Cell Factor (HCF-1) via a consensus HCF-binding motif (HBM) present in E2F4, suggesting a linkage between E2F4 and HCF-1 cell growth pathways

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)