Instance ID10458
Regular Expression[DE]HxY
Motif InstanceDHSY
Bait Uniprot AccessionQ9JJD0
Bait Uniprot IdentifierTHA11_MOUSE
Bait Gene NameThap11
Bait OrganismMus musculus (Mouse)
Sequence Position234-237
Critical ResiduesP4
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Mutation analysis
Interaction ID20458
Interacting DomainGalactose oxidase, central domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)20581084
CommentsThe zinc finger transcriptional regulator, Ronin (Thap11), can interact with the cell growth factor Hcf-1, via a consensus HCF-binding motif (HBM), and together Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of mouse embryonic stem cells


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)