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Instance ID | 10458 | Regular Expression | [DE]HxY | Motif Instance | DHSY | Bait Uniprot Accession | Q9JJD0 | Bait Uniprot Identifier | THA11_MOUSE | Bait Gene Name | Thap11 | Bait Organism | Mus musculus (Mouse) | Sequence Position | 234-237 | Critical Residues | P4 | Motif PTM(s) | Unknown | Secondary Structure | Unknown | Experimental Method(s) | Y2H; Mutation analysis | Interaction ID | 20458 | Interacting Domain | Galactose oxidase, central domain | Disease Association(s) | Unknown | Inhibitor(s) | Unknown | Reference(s) | 20581084 | Comments | The zinc finger transcriptional regulator, Ronin (Thap11), can interact with the cell growth factor Hcf-1, via a consensus HCF-binding motif (HBM), and together Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of mouse embryonic stem cells |
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