Instance ID10469
Regular ExpressionP[MVLIRWY]V[MVLIAS][LM]
Motif InstancePLVLL
Bait Uniprot AccessionP12956
Bait Uniprot IdentifierXRCC6_HUMAN
Bait Gene NameXRCC6
Bait OrganismHomo sapiens (Human)
Sequence Position352-356
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Co-IP; Pull down(GST tag)
Interaction ID20469
Interacting DomainChromo shadow domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11112778
CommentsHuman Ku70 (DNA repair protein XRCC6) interacts with heterochromatin protein 1alpha (HP1 alpha/CBX5) using a HP1-binding motif that interacts with an interface formed by dimerization of two chromoshadow domains in HP1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)