Instance ID10473
Regular ExpressionP[MVLIRWY]V[MVLIAS][LM]
Motif InstancePRVSL
Bait Uniprot AccessionQ62318
Bait Uniprot IdentifierTIF1B_MOUSE
Bait Gene NameTrim28
Bait OrganismMus musculus (Mouse)
Sequence Position486-490
Critical ResiduesP3; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Y2H; Fluorescence technology; Co-IP; Alanine scanning
Interaction ID20473
Interacting DomainChromo shadow domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12154074
CommentsThe PxVxL HP1-binding motif found in the murine transcriptional intermediary factor 1 (TIF1) family protein TIF1beta that interacts with an interface formed by dimerization of two chromoshadow domains of HP1 alpha

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)