Instance ID10474
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceEVSAIVIQRAYRRYLLKQKV
Bait Uniprot AccessionP04775
Bait Uniprot IdentifierSCN2A_RAT
Bait Gene NameScn2a
Bait OrganismRattus norvegicus (Rat)
Sequence Position1906-1925
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Fluorescence polarization spectroscopy; NMR
Interaction ID20474
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21439835
CommentsThe Calmodulin binding IQ motif of the rat Na(V)1.2 voltage-dependent sodium channel (Scn2a) that binds to the apo C-domain of Paramecium Calmodulin (CaM)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)