Instance ID10490
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceAVVLGLVQSLNRQRQKQLL
Bait Uniprot AccessionP40146
Bait Uniprot IdentifierADCY8_RAT
Bait Gene NameAdcy8
Bait OrganismRattus norvegicus (Rat)
Sequence Position1191-1209
Critical ResiduesP7; P8; P12; P14
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Pull down(GST tag)
Interaction ID20490
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19305019
CommentsThe Calmodulin binding IQ motif of the rat Ca(2+)/calmodulin-activated Adenylate cyclase type 8 (Adcy8) that binds to the apo C-domain of rat Calmodulin (CaM)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)