Instance ID10492
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceIKKIKKVQSFMRGWLCRRKW
Bait Uniprot AccessionP70392
Bait Uniprot IdentifierRGRF2_MOUSE
Bait Gene NameRasgrf2
Bait OrganismMus musculus (Mouse)
Sequence Position206-225
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Co-IP
Interaction ID20492
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9032266
CommentsThe Calmodulin binding IQ motif of mouse Ras guanine nucleotide exchange factor 2 (Ras-GRF2) that is required for its apparent constitutive association with calmodulin in epithelial cells ectopically expressing Ras-GRF2


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)