Instance ID10503
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceHKAATKIQASFRGHITRKKL
Bait Uniprot AccessionP06836
Bait Uniprot IdentifierNEUM_BOVIN
Bait Gene NameGAP43
Bait OrganismBos taurus (Bovine)
Sequence Position32-51
Critical ResiduesUnknown
Motif PTM(s)Phosphorylation at Ser-P10
Secondary StructureAlpha helix
Experimental Method(s)Affinity chromatography technology; Mutation analysis; Fluorescence polarization spectroscopy
Interaction ID20503
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)1824693
CommentsInteraction between bovine Neuromodulin (Growth-associated protein 43 or GAP43) and Calmodulin (CaM) via the IQ motif of GAP43 that is disrupted by protein kinase C phosphorylation of neuromodulin at serine 41

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)