Instance ID10506
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceFYATFLIQEHFRKFMKRQEE
Bait Uniprot AccessionQ13698
Bait Uniprot IdentifierCAC1S_HUMAN
Bait Gene NameCACNA1S
Bait OrganismHomo sapiens (Human)
Sequence Position1523-1542
Critical ResiduesP10; P15; P18
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; SPR; X-ray crystallography
Interaction ID20506
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19473981
CommentsHuman Calmodulin (CALM1) binds to the IQ motif in the alpha(1) subunit of human Voltage-gated calcium channel subunit alpha Ca(V)1.1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)