Instance ID10508
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceCVILPEIQKPERKIQFKEK
Bait Uniprot AccessionP38377
Bait Uniprot IdentifierS61A1_CANFA
Bait Gene NameSEC61A1
Bait OrganismCanis familiaris (Dog) (Canis lupus familiaris)
Sequence Position13-31
Critical ResiduesP12
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Fluorescence correlation spectroscopy; Peptide‐spot binding assay; Alanine scanning
Interaction ID20508
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21102557
CommentsThe Calmodulin binding IQ motif in the cytosolic N-terminus of Protein transport protein Sec61 alpha-1 of Canis lupus familiaris that bound CaM but not Ca2+-free apocalmodulin with nanomolar affinity and sequence specificity

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)