Instance ID10509
Regular Expressionxxx[SACLIVTM]xx[ILVMFCT]Qx{3,3}[RK]x{4,5}[RKQ]xx
Motif InstanceEVSAVIIQRAYRRHLLKRTV
Bait Uniprot AccessionP04774
Bait Uniprot IdentifierSCN1A_RAT
Bait Gene NameScn1a
Bait OrganismRattus norvegicus (Rat)
Sequence Position1916-1935
Critical ResiduesP7; P8
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Pull down; Co-IP; Mutation analysis
Interaction ID20509
Interacting DomainEF hand
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)21726526
CommentsThe ubiquitous calcium sensor calmodulin (CaM) binds to the IQ Motif of rat brain Voltage-gated sodium channel subunit alpha Nav1.1


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)