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| Instance ID | 10511 | | Regular Expression | [LM]YPxxx[LI][^P][^P][LI] | | Motif Instance | LYPLTSLRSL | | Bait Uniprot Accession | P03347 | | Bait Uniprot Identifier | GAG_HV1B1 | | Bait Gene Name | gag | | Bait Organism | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) | | Sequence Position | 495-504 | | Critical Residues | P2; P3 | | Motif PTM(s) | Unknown | | Secondary Structure | Alpha helix | | Experimental Method(s) | Mutation analysis; SPR; Y2H; Pull down; ITC; X-ray crystallography | | Interaction ID | 20511 | | Interacting Domain | V-domain | | Disease Association(s) | Human immunodeficiency virus (HIV) infection | | Inhibitor(s) | Unknown | | Reference(s) | 17350572, 14519844, 14505569, 17277784, 18066081 | | Comments | Efficient budding of retroviruses such as HIV-1 requires short peptide motifs, known as late domains, in the viral Gag protein, that recruits human ALIX (AIP1/PDCD6IP) |
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