Instance ID10523
Regular Expression[KR]{0,2}[KR]x{0,2}[KR]x{2,4}[ILVM]x[ILVF]
Motif InstanceRRAKGAMGL
Bait Uniprot AccessionP28562
Bait Uniprot IdentifierDUS1_HUMAN
Bait Gene NameDUSP1
Bait OrganismHomo sapiens (Human)
Sequence Position54-62
Critical ResiduesP1; P2
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Y2H; Co-IP
Interaction ID20523
Interacting DomainProtein kinase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11278799, 11953434
CommentsMAPK docking motif in human Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1/CL100/DUSP1) that mediates binding to human MAP kinase 1 (or ERK-2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)