Instance ID10539
Regular ExpressionFxFP
Motif InstanceFNFP
Bait Uniprot AccessionP28562
Bait Uniprot IdentifierDUS1_HUMAN
Bait Gene NameDUSP1
Bait OrganismHomo sapiens (Human)
Sequence Position339-342
Critical ResiduesP1; P3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation analysis; Pull down(GST tag)
Interaction ID20539
Interacting DomainProtein kinase domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)9925641, 16286470
CommentsThe FXFP motif in human Mitogen-activated protein (MAP) kinase phosphatase 1 (MKP-1/CL100/DUSP1) that mediates binding to human MAP kinase 1 (or ERK-2)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)