Instance ID10541
Regular ExpressionPxLxP
Motif InstancePNLVP
Bait Uniprot AccessionP03255
Bait Uniprot IdentifierE1A_ADE05
Bait Gene NameNot Available
Bait OrganismHuman adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Sequence Position113-117
Critical ResiduesP3
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Mutation disrupting interaction; Mutation analysis; Co-IP; Pull down(GST tag)
Interaction ID20541
Interacting DomainMYND domain
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)11733528
CommentsThe conserved Mynd domain of human protein BS69 (ZMYND11) binds the adenoviral E1A oncoprotein through a PxLxP motif

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)