Instance ID10552
Regular Expression[LMV]PxLE
Motif InstanceMPDLE
Bait Uniprot AccessionQ15185
Bait Uniprot IdentifierTEBP_HUMAN
Bait Gene NamePTGES3
Bait OrganismHomo sapiens (Human)
Sequence Position156-160
Critical ResiduesP2; P4; P5
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)Alanine scanning; Mutation analysis; Western blot; RNA interference; Co-IP; Mass spectrometry; Co-IP
Interaction ID20552
Interacting DomainMYND domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)23413029
CommentsThe MYND-type Zinc Finger of human Prolyl hydroxylase domain protein 2 (PHD2/EGLN1) binds a PxLE motif found in human HSP90 co-chaperone p23 (PTGES3)


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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)