Instance ID10553
Regular Expression[LMV]PxLE
Motif InstanceLPPLE
Bait Uniprot AccessionQ14318
Bait Uniprot IdentifierFKBP8_HUMAN
Bait Gene NameFKBP8
Bait OrganismHomo sapiens (Human)
Sequence Position52-56
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureUnknown
Experimental Method(s)FRET; subcellular preparation; Colocalization; Pull down; Mutation analysis; ITC; Fluorescence polarization spectroscopy; Competition binding; Affinity chromatography technology; protein array; Co-IP; Mass spectrometry
Interaction ID20553
Interacting DomainMYND domain
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)19546213, 23413029
CommentsThe MYND-type Zinc Finger of human Prolyl hydroxylase domain protein 2 (PHD2/EGLN1) binds a PxLE motif found in human Peptidyl-prolyl cis-trans isomerase FKBP8 (or FKBP38)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)