Instance ID10556
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceVLRKLLK
Bait Uniprot AccessionQ90ZL7
Bait Uniprot IdentifierQ90ZL7_DANRE
Bait Gene Nameprox1a
Bait OrganismDanio rerio (Zebrafish) (Brachydanio rerio)
Sequence Position69-75
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Site-directed mutagenesis; Y2H
Interaction ID20556
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)14517294
CommentsThe NR box motif (LXXLL) of Zebrafish Prox1, a prospero-related homeodomain protein, interacts with and modulates the transcriptional activity of Ff1b (nr5a4), the zebrafish homologue of SF-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)