Instance ID10558
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceELKALLQ
Bait Uniprot AccessionQ9UQ80
Bait Uniprot IdentifierPA2G4_HUMAN
Bait Gene NamePA2G4
Bait OrganismHomo sapiens (Human)
Sequence Position353-359
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Pull down(GST tag)
Interaction ID20558
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Cancer
Inhibitor(s)Unknown
Reference(s)12165860
CommentsThe NR box motif (LXXLL) of human ErbB-3 binding protein (EBP1)/ Proliferation-associated protein 2G4 (PA2G4), that is necessary for binding the human Androgen receptor (AR)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)