Instance ID10567
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceILHRLLQ
Bait Uniprot AccessionQ15596
Bait Uniprot IdentifierNCOA2_HUMAN
Bait Gene NameNCOA2
Bait OrganismHomo sapiens (Human)
Sequence Position689-695
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)X-ray crystallography; Affinity chromatography technology; Mutation analysis
Interaction ID20567
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)11937504, 9430642
CommentsThe NR box motif (689-695) of human Nuclear receptor coactivator 2 (NCOA2)/ Transcriptional intermediary factor 2 (TIF2) that is necessary for binding the human Glucocorticoid receptor (GRL/NR3C1)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)