Instance ID10569
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceLLKKLLL
Bait Uniprot AccessionQ9UBK2
Bait Uniprot IdentifierPRGC1_HUMAN
Bait Gene NamePPARGC1A
Bait OrganismHomo sapiens (Human)
Sequence Position143-149
Critical ResiduesUnknown
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)X-ray crystallography
Interaction ID20569
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)18469005, 12502716
CommentsThe functional interaction between the human Peroxisome proliferator-activated receptor gamma (PPARG) and its coactivator PPAR-gamma coactivator 1-alpha (PPARGC1A/PGC-1) is mediated by the LXXLL motif of PGC-1

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)