Instance ID10571
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceRLCRLLR
Bait Uniprot AccessionO43593
Bait Uniprot IdentifierHAIR_HUMAN
Bait Gene NameHR
Bait OrganismHomo sapiens (Human)
Sequence Position565-571
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Y2H; Co-IP; Pull down(GST tag)
Interaction ID20571
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12215540
CommentsThe NR box motif (565-571) of human product of the thyroid hormone-regulated mammalian gene hairless (HR) that is necessary for binding the human Nuclear receptor ROR-alpha (RORA)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)