Instance ID10573
Regular Expression[^P]L[^P][^P]LL[^P]
Motif InstanceILTSLLQ
Bait Uniprot AccessionQ15648
Bait Uniprot IdentifierMED1_HUMAN
Bait Gene NameMED1
Bait OrganismHomo sapiens (Human)
Sequence Position603-609
Critical ResiduesP5; P6
Motif PTM(s)Unknown
Secondary StructureAlpha helix
Experimental Method(s)Mutation analysis; Y2H
Interaction ID20573
Interacting DomainLigand-binding domain of nuclear hormone receptor
Disease Association(s)Unknown
Inhibitor(s)Unknown
Reference(s)12556447
CommentsThe NR box motif (603-609) of human Mediator complex subunit 1 (MED1/TRAP220) that is necessary for binding the human Peroxisome proliferator-activated receptor gamma (PPARG)

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For queries, suggestions and submission of novel motifs please contact Dr. Sudipto Saha (ssaha4@jcbose.ac.in)